Through the nanocarrier targeted transport technology, Kopexil and Kopyrrol double packages are loaded on the carrier with very small particle size, making it easier to penetrate into the deep skin, and deliver the right amount of efficacy ingredients to the right place at the right time, so as to achieve the effect of double efficacy, fast penetration and high stability. This product has good water solubility and transparency, suitable for a variety of formulations and high stability, not easily affected by light, heat, and temperature.